发明授权
- 专利标题: Tracking of bone marrow cells for metastasis screening
- 专利标题(中): 跟踪骨髓细胞进行转移筛选
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申请号: US12974214申请日: 2010-12-21
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公开(公告)号: US08747839B2公开(公告)日: 2014-06-10
- 发明人: Christian Geppert , Arne Hengerer , Sven Meyburg , Sebastian Schmidt , Susanne Schmolke , Ralph Markus Wirtz
- 申请人: Christian Geppert , Arne Hengerer , Sven Meyburg , Sebastian Schmidt , Susanne Schmolke , Ralph Markus Wirtz
- 申请人地址: DE Munich DE Marburg
- 专利权人: Siemens Aktiengesellschaft,Siemens Healthcare Diagnostics Products GmbH
- 当前专利权人: Siemens Aktiengesellschaft,Siemens Healthcare Diagnostics Products GmbH
- 当前专利权人地址: DE Munich DE Marburg
- 代理机构: Harness, Dickey & Pierce, P.L.C.
- 优先权: DE102009060317 20091223
- 主分类号: A01N63/02
- IPC分类号: A01N63/02 ; A61K35/32 ; A61K51/02 ; A61B5/055
摘要:
At least one embodiment of the invention relates to bone marrow precursor cells or bone marrow cells of a patient, the cells labeled with at least one contrast agent suitable for an imaging method, for use in an imaging method for diagnosing a metastasizing cancer, wherein the local accumulation of the labeled precursor cells or bone marrow cells indicates the presence of a metastasizing tumor growth. At least one embodiment also relates to a method for imaging a metastasizing tumor tissue in a patient, wherein a) bone marrow precursor cells or bone marrow cells are extracted from a patient, b) these precursor cells or bone marrow cells are labeled with at least one contrast agent suitable for an imaging method, c) the precursor cells or bone marrow cells thus labeled are retransplanted or reinjected into the patient, and d) the presence of metastasizing tumor cells is depicted with an imaging method. At least one embodiment also relates a method for imaging a metastasizing tumor tissue, wherein a suitable imaging method is used to image bone marrow precursor cells and/or bone marrow cells that are accumulated in a metastasizing tumor tissue and labeled with at least one contrast agent suitable for an imaging method.
公开/授权文献
- US20110150758A1 TRACKING OF BONE MARROW CELLS FOR METASTASIS SCREENING 公开/授权日:2011-06-23
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