发明授权
- 专利标题： Hepatitis B virus compositions and methods of use
- 专利标题（中）： 乙型肝炎病毒组合物和使用方法
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申请号： US12526759申请日： 2008-02-20
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公开(公告)号： US08748373B2公开(公告)日： 2014-06-10
- 发明人: Ning Chai , John M. Taylor
- 申请人： Ning Chai , John M. Taylor
- 申请人地址： US PA Philadelphia
- 专利权人： Fox Chase Cancer Center
- 当前专利权人： Fox Chase Cancer Center
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Riverside Law LLP
- 国际申请： PCT/US2008/002236 WO 20080220
- 国际公布： WO2008/103380 WO 20080828
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A01N37/18 ; A61P1/16 ; A61P31/12 ; A61K38/16 ; A61K39/00 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00 ; C12P21/08 ; C12N7/00 ; C12N7/01
摘要：
A polypeptide comprising a preS1 region of hepatitis B virus (HBV), or a fragment thereof, and/or the preS2 region of HBV or a fragment thereof, and methods of use to inhibit virus infection are disclosed. A lentivirus comprising hepatitis B virus (HBV) envelope proteins, or a fragment thereof, and/or the L envelope protein of HBV and/or the M envelope protein of HBV or a fragment thereof, and/or the S envelope protein of HBV or a fragment thereof, and methods of use of this lentivirus HBV pseudovirus as a gene therapy to target hepatocytes for the administration of therapeutic agents are also disclosed.
公开/授权文献
- US20110257080A1 Hepatitis B Virus Compositions and Methods of Use 公开/授权日：2011-10-20
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