发明授权
US08748627B2 Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
失效
乙酰辅酶A羧化酶(ACC)抑制剂及其在糖尿病,肥胖症和代谢综合征中的应用
- 专利标题: Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
- 专利标题(中): 乙酰辅酶A羧化酶(ACC)抑制剂及其在糖尿病,肥胖症和代谢综合征中的应用
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申请号: US11675410申请日: 2007-02-15
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公开(公告)号: US08748627B2公开(公告)日: 2014-06-10
- 发明人: Yu Gui Gu , Moshe Weitzberg , Xiangdong Xu , Richard F. Clark , Tianyuan Zhang , Qun Li , Todd M. Hansen , Hing Sham , Bruce A. Beutel , Heidi S. Camp , Xiaojun Wang
- 申请人: Yu Gui Gu , Moshe Weitzberg , Xiangdong Xu , Richard F. Clark , Tianyuan Zhang , Qun Li , Todd M. Hansen , Hing Sham , Bruce A. Beutel , Heidi S. Camp , Xiaojun Wang
- 申请人地址: US IL North Chicago
- 专利权人: AbbVie Inc.
- 当前专利权人: AbbVie Inc.
- 当前专利权人地址: US IL North Chicago
- 代理机构: Michael Best & Friedrich LLP
- 代理商 Lisa V. Mueller
- 主分类号: A61K31/427
- IPC分类号: A61K31/427 ; A61K31/433 ; A61K31/4245 ; A61K31/4439 ; A61K31/444 ; C07D417/12 ; C07D417/14 ; C07D417/04 ; C07D413/12 ; C07D413/14
摘要:
The present invention relates to compounds of formula (I), which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
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