发明授权
- 专利标题： Bone morphogenic protein binding peptide
- 专利标题（中）： 骨形态发生蛋白结合肽
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申请号： US13481648申请日： 2012-05-25
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公开(公告)号： US08759296B2公开(公告)日： 2014-06-24
- 发明人: Samuel S. Murray , Keyvan Behnam , Elsa J. Brochmann-Murray
- 申请人： Samuel S. Murray , Keyvan Behnam , Elsa J. Brochmann-Murray
- 申请人地址： US CA Oakland US DC Washington
- 专利权人： The Regents of The University of California,The United States of America as Represented by The Department of Veterans Affairs
- 当前专利权人： The Regents of The University of California,The United States of America as Represented by The Department of Veterans Affairs
- 当前专利权人地址： US CA Oakland US DC Washington
- 代理机构： McDermott Will & Emery LLP
- 主分类号： A61K38/10
- IPC分类号： A61K38/10 ; A61K38/12 ; A61K38/18 ; A61K35/32 ; C07K4/12 ; C07K5/12 ; C07K14/51 ; C07K14/495 ; C12N5/077
摘要：
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the overall osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.
公开/授权文献
- US20130095075A1 BONE MORPHOGENIC PROTEIN BINDING PEPTIDE 公开/授权日：2013-04-18