Invention Grant
US08759388B2 Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
有权
β-和γ-氨基 - 异喹啉酰胺化合物和取代的苯甲酰胺化合物
- Patent Title: Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
- Patent Title (中): β-和γ-氨基 - 异喹啉酰胺化合物和取代的苯甲酰胺化合物
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Application No.: US13442263Application Date: 2012-04-09
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Publication No.: US08759388B2Publication Date: 2014-06-24
- Inventor: Mitchell A. deLong , Jill Marie Sturdivant , Susan M. Royalty
- Applicant: Mitchell A. deLong , Jill Marie Sturdivant , Susan M. Royalty
- Applicant Address: US NC Research Triangle Park
- Assignee: Aerie Pharmaceuticals, Inc.
- Current Assignee: Aerie Pharmaceuticals, Inc.
- Current Assignee Address: US NC Research Triangle Park
- Agency: Michael Best & Friedrich LLP
- Main IPC: A61K31/381
- IPC: A61K31/381 ; A61K31/16 ; C07D333/22 ; C07C237/48
Abstract:
Disclosed are beta and gamma-amino isoquinoline amide compounds and substituted benzamide compounds. In particular, the invention provides compounds that affect the function of kinases in a cell and that are useful as therapeutic agents or with therapeutic agents. The compounds of the invention are useful in the treatment of a variety of diseases and conditions including eye diseases such as glaucoma, cardiovascular diseases, and diseases characterized by abnormal growth, such as cancers. The invention further provides compositions containing the beta or gamma-amino isoquinoline amide compounds or substituted benzamide compounds.
Public/Granted literature
- US20120196916A1 BETA- AND GAMMA-AMINO-ISOQUINOLINE AMIDE COMPOUNDS AND SUBSTITUTED BENZAMIDE COMPOUNDS Public/Granted day:2012-08-02
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