A wearable tubing safety vest configured to harness medical treatment delivery tubing and/or communication cables. The tubing safety vest comprises a vest component having a body-encompassing component cooperable with a plurality of releasably securable flaps, and an elongate tubing harness configured to releasably receive and retain therethrough at least one of medical treatment delivery tubing and communication cables. The tubing harness may be securely engaged with the vest component or alternatively, at least one hinge component can be interposed the vest component and the tubing harness. The vest component is configured for demountably encircling a mammalian body torso, e.g, a human infant torso, juvenile torso, or an adult torso. The tubing harness may be demountably engaged with the front or with the back of the vest component. The wearble tubing safety vest may be optionally configured for demountable engagement about an animal's torso.