Invention Grant
- Patent Title: PSMA-binding agents and uses thereof
- Patent Title (中): PSMA结合剂及其用途
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Application No.: US13057044Application Date: 2009-07-31
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Publication No.: US08778305B2Publication Date: 2014-07-15
- Inventor: Martin Pomper , Ronnie Charles Mease , Ying Chen
- Applicant: Martin Pomper , Ronnie Charles Mease , Ying Chen
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agent Jeffrey W. Childers
- International Application: PCT/US2009/052456 WO 20090731
- International Announcement: WO2010/014933 WO 20100204
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61K49/00
Abstract:
Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.
Public/Granted literature
- US20110142760A1 PSMA-BINDING AGENTS AND USES THEREOF Public/Granted day:2011-06-16
Information query
