发明授权
- 专利标题: Bone formation agent and method of production
- 专利标题(中): 骨形成剂及生产方法
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申请号: US10561800申请日: 2004-06-25
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公开(公告)号: US08778374B2公开(公告)日: 2014-07-15
- 发明人: Dieter Reif , Fabian Peters , Frank Palm , Joachim Wittner
- 申请人: Fabian Peters , Frank Palm , Joachim Wittner , Ute Reif
- 申请人地址: DE Frankfurt/Main
- 专利权人: Curasan AG
- 当前专利权人: Curasan AG
- 当前专利权人地址: DE Frankfurt/Main
- 代理机构: Roylance, Abrams, Berdo & Goodman, L.L.P.
- 优先权: DE10328892 20030626
- 国际申请: PCT/EP2004/006947 WO 20040625
- 国际公布: WO2004/112855 WO 20041229
- 主分类号: A61F2/00
- IPC分类号: A61F2/00 ; A61F13/00 ; C04B35/447
摘要:
The invention relates to a bone formation agent of porous calcium phosphate having an isotropic sintered structure and, between the particles of the calcium phosphate, statistically distributed pores in a plurality of discrete size ranges. The bone formation agent has at least two, preferably three, discrete pore size distributions. Its porosity has an irregular geometric shape. The sintered particles of the calcium phosphate have a particle size smaller than 63 μm with a d50 value in the range from 5 to 20 μm. The interconnecting pore share in the overall porosity is limited to pore sizes less than 10 μm. The bone formation agent can be used in the form of a granulate or shaped body for bone regeneration. In the case of granulates, the maximum pore diameters are matched to the granulate diameter. The invention relates also to a method of producing the bone formation agent.
公开/授权文献
- US20070218098A1 Bone Formation Agent And Method Of Production 公开/授权日:2007-09-20
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