Invention Grant
- Patent Title: Substituted pyridine, pyridazine, pyrazine and pyrimidine compounds and methods for using the same
- Patent Title (中): 取代的吡啶，哒嗪，吡嗪和嘧啶化合物及其使用方法
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Application No.: US13194810Application Date: 2011-07-29
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Publication No.: US08791136B2Publication Date: 2014-07-29
- Inventor: Dane Goff , Donald Payan , Rajinder Singh , Simon Shaw , David Carroll , Yasumichi Hitoshi
- Applicant: Dane Goff , Donald Payan , Rajinder Singh , Simon Shaw , David Carroll , Yasumichi Hitoshi
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Agent Travis Young
- Main IPC: A61K31/4427
- IPC: A61K31/4427 ; C07D401/14
Abstract:
Disclosed are substituted pyridine compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure wherein E, J, T, the ring system denoted by “B”, T, R3, R4, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.
Public/Granted literature
- US20120028954A1 Substituted Pyridine, Pyridazine, Pyrazine And Pyrimidine Compounds And Methods For Using The Same Public/Granted day:2012-02-02
Information query
IPC分类:
