Invention Grant
- Patent Title: TLR-2 agonists and methods of use thereof
- Patent Title (中): TLR-2激动剂及其使用方法
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Application No.: US13470554Application Date: 2012-05-14
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Publication No.: US08795678B2Publication Date: 2014-08-05
- Inventor: Shu-Mei Liang , Yu-Ching Chang
- Applicant: Shu-Mei Liang , Yu-Ching Chang
- Applicant Address: TW Taipei
- Assignee: Academia Sinica
- Current Assignee: Academia Sinica
- Current Assignee Address: TW Taipei
- Agency: Bozicevic, Field & Francis LLP
- Agent Pamela J. Sherwood
- Main IPC: A61K39/39
- IPC: A61K39/39 ; A61K39/145 ; A61K39/295
Abstract:
Two new TLR2 agonists, VP1 and VP3, which are structural proteins of FMDV. Residues of VP3 responsible for TLR2 activation are identified. In vivo experiments showed that VP3-4xM2e is active as a vaccine adjuvant.
Public/Granted literature
- US20120294878A1 TLR-2 AGONISTS AND METHODS OF USE THEREOF Public/Granted day:2012-11-22
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