发明授权
- 专利标题: Feedback prodrug
- 专利标题(中): 反馈前药
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申请号: US13222495申请日: 2011-08-31
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公开(公告)号: US08796229B2公开(公告)日: 2014-08-05
- 发明人: Geert-Jan Boons , Jun Guo
- 申请人: Geert-Jan Boons , Jun Guo
- 申请人地址: US GA Athens
- 专利权人: University of Georgia Research Foundation, Inc.
- 当前专利权人: University of Georgia Research Foundation, Inc.
- 当前专利权人地址: US GA Athens
- 代理机构: Mueting, Raasch & Gebhardt, P.A.
- 主分类号: A61K47/00
- IPC分类号: A61K47/00 ; A61K47/48
摘要:
Compounds and methods for use in selectively inhibiting a lytic enzyme based on feedback inhibition are described. The conjugated compound serves as a substrate for a lytic enzyme. Cleavage of the conjugated compound by the lytic enzyme releases an inhibitor of the enzyme.
公开/授权文献
- US20120058960A1 FEEDBACK PRODRUG 公开/授权日:2012-03-08
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