Invention Grant
- Patent Title: 1,3,4-Oxadiazole-2-carboxamide compound
- Patent Title (中): 1,3,4-恶二唑-2-甲酰胺化合物
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Application No.: US13519707Application Date: 2010-12-28
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Publication No.: US08796320B2Publication Date: 2014-08-05
- Inventor: Akira Asai , Kenji Matsuno , Naohisa Ogo , Osamu Takahashi , Yoshiaki Masuda , Ayumu Muroya , Yasuto Akiyama , Tadashi Ashizawa , Tadashi Okawara
- Applicant: Akira Asai , Kenji Matsuno , Naohisa Ogo , Osamu Takahashi , Yoshiaki Masuda , Ayumu Muroya , Yasuto Akiyama , Tadashi Ashizawa , Tadashi Okawara
- Applicant Address: JP Mishima-shi JP Tokyo JP Shizuoka JP Kumamoto-shi JP Tokyo
- Assignee: General Incorporated Association Pharma Valley Project Supporting Organization,Pharma Design,Shizuoka Prefecture,Kumamoto Health Science University,Kabushiki Kaisha Yakult Honsha
- Current Assignee: General Incorporated Association Pharma Valley Project Supporting Organization,Pharma Design,Shizuoka Prefecture,Kumamoto Health Science University,Kabushiki Kaisha Yakult Honsha
- Current Assignee Address: JP Mishima-shi JP Tokyo JP Shizuoka JP Kumamoto-shi JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2009-297960 20091228
- International Application: PCT/JP2010/073787 WO 20101228
- International Announcement: WO2011/081205 WO 20110707
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; C07D271/10 ; C07D413/14
Abstract:
Provided is a 1,3,4-oxadiazole-2-carboxamide compound which has STAT3 inhibitory activity and is useful as an anticancer agent. Provided is a 1,3,4-oxadiazole-2-carboxamide compound represented by formula (I) or a pharmacologically acceptable salt thereof (in the formula, Ar represents a furyl group or the like; R1 represents a hydrogen atom or the like; and —X—Y represents a diaryl group such as a biphenyl group).
Public/Granted literature
- US20120302524A1 1,3,4-OXADIAZOLE-2-CARBOXAMIDE COMPOUND Public/Granted day:2012-11-29
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