发明授权
US08798707B2 Flexible, multi-channel microelectrode for recording laboratory animal EEG and method for recording laboratory animal EEG using the same
有权
用于记录实验室动物脑电的灵活的多通道微电极和使用该实验室动物脑电图记录实验动物脑电图的方法
- 专利标题: Flexible, multi-channel microelectrode for recording laboratory animal EEG and method for recording laboratory animal EEG using the same
- 专利标题(中): 用于记录实验室动物脑电的灵活的多通道微电极和使用该实验室动物脑电图记录实验动物脑电图的方法
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申请号: US13123217申请日: 2008-12-24
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公开(公告)号: US08798707B2公开(公告)日: 2014-08-05
- 发明人: Ji Hyun Choi , Hee Sup Shin , Klaus Peter Koch
- 申请人: Ji Hyun Choi , Hee Sup Shin , Klaus Peter Koch
- 申请人地址: KR
- 专利权人: Korea Institute of Science and Technology
- 当前专利权人: Korea Institute of Science and Technology
- 当前专利权人地址: KR
- 代理机构: Cantor Colburn LLP
- 优先权: KR10-2008-0098655 20081008
- 国际申请: PCT/KR2008/007671 WO 20081224
- 国际公布: WO2010/041794 WO 20100415
- 主分类号: A61B5/0478
- IPC分类号: A61B5/0478
摘要:
Disclosed are a novel, elastic, biocompatible, micro-sized, polyimide-based multi-channel microelectrode for recording of electroencephalography (EEG) from a laboratory animal including mouse, and a method for recording of laboratory animal EEG using the microelectrode. The microelectrode may include 2 grounding electrodes and 32 recording electrodes. A connector for signal transmission easily connects the microelectrode to a signal acquiring apparatus. The total weight of the microelectrode, including the connector, does not exceed 150 mg. Laboratory animal EEG, including that of mouse, provides the advantage of monitoring the brain state of a freely moving animal following a genetic or pharmaceutical manipulation. The microelectrode can be implanted without surgery and may be detached from wires while EEG is not recorded from the laboratory animal. The microelectrode can successfully acquire broadband EEG signals from the skull of the laboratory animal and is effective in monitoring spatial and temporal pattern of brain activities of the laboratory animal.
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