A mobile server system with an energy regeneration function includes a container, at least one server placed within the container, and at least one power generating mechanism received in the receiving portion. Top surface defines a receiving portion. The container defines a through hole communicating with the receiving portion in a position where the at least one server is placed. The power generating mechanism includes an impeller element, a generator and a shaft fixed between the impeller element and the generator. Hot air generated from the at least one server is transmitted to the receiving portion through the through hole to cooperate with cold air from the air to generate airflow. The airflow drives the impeller element to rotate. The shaft is driven by the impeller element to rotate. The generator is driven by the shaft to rotate to generate power.