发明授权
- 专利标题： Method of inhibiting miR-33 using a modified oligonucleotide
- 专利标题（中）： 使用修饰的寡核苷酸抑制miR-33的方法
-
申请号： US13540097申请日： 2012-07-02
-
公开(公告)号： US08809294B2公开(公告)日： 2014-08-19
- 发明人: Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta
- 申请人： Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta
- 申请人地址： US CA San Diego
- 专利权人： Regulus Therapeutics Inc.
- 当前专利权人： Regulus Therapeutics Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Casimir Jones, S.C.
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C07H21/04
摘要：
Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.
公开/授权文献
信息查询
IPC分类:
