发明授权
US08809321B2 Diaryl ether linked pyrrolo [2,1-c][1,4] benzodiazepine hybrids and process for the preparation thereof
有权
二芳基醚连接的吡咯并[2,1-c] [1,4]苯并二氮杂杂环化合物及其制备方法
![Diaryl ether linked pyrrolo [2,1-c][1,4] benzodiazepine hybrids and process for the preparation thereof](/docs/US/2014-08-19/US08809321B2/abs.jpg.600x600.jpg)
- 专利标题： Diaryl ether linked pyrrolo [2,1-c][1,4] benzodiazepine hybrids and process for the preparation thereof
- 专利标题（中）： 二芳基醚连接的吡咯并[2,1-c] [1,4]苯并二氮杂杂环化合物及其制备方法
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申请号： US13256601申请日： 2011-03-30
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公开(公告)号： US08809321B2公开(公告)日： 2014-08-19
- 发明人: Ahmed Kamal , Arutla Viswanath , Jayanti Naga Srirama Chandra Murty , Earla Vijaya Bharathi , Gadupudi Ramakrishna , Farheen Sulthana
- 申请人： Ahmed Kamal , Arutla Viswanath , Jayanti Naga Srirama Chandra Murty , Earla Vijaya Bharathi , Gadupudi Ramakrishna , Farheen Sulthana
- 申请人地址： IN New Delhi
- 专利权人： Council of Scientific and Industrial Research
- 当前专利权人： Council of Scientific and Industrial Research
- 当前专利权人地址： IN New Delhi
- 代理机构： Knobbe Martens Olson & Bear, LLP.
- 优先权： IN390/DEL/2011 20110215
- 国际申请： PCT/IB2011/000670 WO 20110330
- 国际公布： WO2012/110840 WO 20120823
- 主分类号： C07D487/00
- IPC分类号： C07D487/00 ; A61K31/407 ; A61P35/00
![Diaryl ether linked pyrrolo [2,1-c][1,4] benzodiazepine hybrids and process for the preparation thereof](/abs-image/US/2014/08/19/US08809321B2/abs.jpg.150x150.jpg)
摘要：
The present invention provides a compound of general formula A, useful as potential anticancer agents against eleven human cancer cell lines. The present invention further provides a process for the preparation of diaryl ether linked pyrrolo[2,1-c][1,4]benzodi azepine conjugates attached through different alkane spacers of general formula A.
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