Invention Grant
- Patent Title: Serine/threonine kinase inhibitors
- Patent Title (中): 丝氨酸/苏氨酸激酶抑制剂
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Application No.: US13723770Application Date: 2012-12-21
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Publication No.: US08815877B2Publication Date: 2014-08-26
- Inventor: Ignacio Aliagas-Martin , James Crawford , Wendy Lee , Simon Mathieu , Joachim Rudolph
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Brian L. Buckwalter
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61K31/505

Abstract:
Compounds having the formula I wherein A, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, Ra, Rb, X1, X2, X3 and n are as defined herein are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.
Public/Granted literature
- US20130178486A1 SERINE/THREONINE KINASE INHIBITORS Public/Granted day:2013-07-11
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