Invention Grant
US08815926B2 Substituted pyrrolo[3,4-D]imidazoles for the treatment of MDM2/4 mediated diseases
有权
取代的吡咯并[3,4-D]咪唑用于治疗MDM2 / 4介导的疾病
![Substituted pyrrolo[3,4-D]imidazoles for the treatment of MDM2/4 mediated diseases](/docs/US/2014-08-26/US08815926B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrrolo[3,4-D]imidazoles for the treatment of MDM2/4 mediated diseases
- Patent Title (中): 取代的吡咯并[3,4-D]咪唑用于治疗MDM2 / 4介导的疾病
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Application No.: US13748790Application Date: 2013-01-24
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Publication No.: US08815926B2Publication Date: 2014-08-26
- Inventor: Pascal Furet , Vito Guagnano , Philipp Holzer , Joerg Kallen , Lv Liao , Robert Mah , Liang Mao , Keiichi Masuya , Achim Schlapbach , Stefan Stutz , Andrea Vaupel
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Scott W. Reid
- Main IPC: A61K31/4188
- IPC: A61K31/4188 ; C07D235/02 ; C07D487/04 ; A61K45/06 ; A61K31/541 ; A61K31/4439 ; A61K31/506 ; A61K31/5377 ; A61K31/501
![Substituted pyrrolo[3,4-D]imidazoles for the treatment of MDM2/4 mediated diseases](/abs-image/US/2014/08/26/US08815926B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to compounds of formula (I): as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.
Public/Granted literature
- US20140011798A1 IMIDAZOPYRROLIDINONE COMPOUNDS Public/Granted day:2014-01-09
Information query
IPC分类:
