发明授权
US08822480B2 Bicyclic heterocycle derivatives and use thereof as GPR119 modulators
有权
双环杂环衍生物及其作为GPR119调节剂的用途
- 专利标题： Bicyclic heterocycle derivatives and use thereof as GPR119 modulators
- 专利标题（中）： 双环杂环衍生物及其作为GPR119调节剂的用途
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申请号： US13003681申请日： 2009-07-15
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公开(公告)号： US08822480B2公开(公告)日： 2014-09-02
- 发明人: Santhosh Francis Neelamkavil , Craig D. Boyle , Samuel Chackalamannil , William J. Greenlee , Bernard R. Neustadt , Andrew W. Stamford
- 申请人： Santhosh Francis Neelamkavil , Craig D. Boyle , Samuel Chackalamannil , William J. Greenlee , Bernard R. Neustadt , Andrew W. Stamford
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Anna L. Cocuzzo; Catherine D. Fitch
- 国际申请： PCT/US2009/050633 WO 20090715
- 国际公布： WO2010/009195 WO 20100121
- 主分类号： C07D519/00
- IPC分类号： C07D519/00 ; A61K31/519 ; A61P13/12 ; A61P3/04
摘要：
The present invention relates to Bicyclic Heterocycle Derivatives of Formula (I), compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of a G-protein coupled receptor (GPCR) such as GPR119 in a patient.
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