Invention Grant
US08828992B2 Substituted azole derivatives, pharmaceutical composition containing the derivatives, and method for treating Parkinson's disease using the same
有权
取代的唑衍生物，含有衍生物的药物组合物，以及使用其衍生物治疗帕金森病的方法
- Patent Title: Substituted azole derivatives, pharmaceutical composition containing the derivatives, and method for treating Parkinson's disease using the same
- Patent Title (中): 取代的唑衍生物，含有衍生物的药物组合物，以及使用其衍生物治疗帕金森病的方法
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Application No.: US13202449Application Date: 2010-02-25
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Publication No.: US08828992B2Publication Date: 2014-09-09
- Inventor: Cheol-Hyoung Park , Hye-Kyung Min , Mi-Jung Lim , Ji-Won Lee , Jin-Yong Chung , Choon-Ho Ryu , Yeo-Jin Yoon , Mi-Kyung Ji , Joo-Young Park
- Applicant: Cheol-Hyoung Park , Hye-Kyung Min , Mi-Jung Lim , Ji-Won Lee , Jin-Yong Chung , Choon-Ho Ryu , Yeo-Jin Yoon , Mi-Kyung Ji , Joo-Young Park
- Applicant Address: KR Seoul
- Assignee: SK Biopharmaceuticals Co., Ltd.
- Current Assignee: SK Biopharmaceuticals Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: KR10-2009-0015856 20090225; KR10-2010-0016686 20100224
- International Application: PCT/KR2010/001186 WO 20100225
- International Announcement: WO2010/098600 WO 20100902
- Main IPC: A61K31/551
- IPC: A61K31/551 ; A61K31/5377 ; A61K31/4439 ; A61K31/42 ; C07D413/06 ; C07D413/12 ; C07D261/08 ; C07D263/32 ; C07D277/02 ; A61K45/06 ; C07D249/10 ; A61K31/554 ; A61K31/16 ; A61K31/198
Abstract:
Provided are a substituted azole derivative and pharmaceutically acceptable salts thereof, a pharmaceutical composition including an effective amount of the derivative, and a method for treating Parkinson's disease in a mammal including administering an effective amount of the compound to the mammal. The azole derivative of the following Formula (I) and pharmaceutically useful salts thereof have an efficacy against Parkinson's disease from inhibitory effects of the activity of MAO-B.
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