A method and system for estimating the inflation pressure of a tire in which data representative of the deformation undergone by the tire on a rolling surface are obtained. The obtained data are processed so as to obtain a first quantity representative of the extent of the deformation within a first deformation region substantially corresponding to the footprint between the tire and the rolling surface and a second quantity, different from the first quantity, representing the extent of the deformation in a second deformation region, said second region including the first deformation region and having a circumferential extension greater than the circumferential extension of the first deformation region, the second quantity being obtained starting from at least a part of the obtained data, which corresponds to a portion of said second deformation region that is external to the footprint. The pressure is estimated based on the first quantity and the second quantity thus obtained.