发明授权
- 专利标题： 5-lipoxygenase-activating protein (FLAP) inhibitors
- 专利标题（中）： 5-脂氧合酶激活蛋白（FLAP）抑制剂
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申请号： US12089706申请日： 2006-11-03
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公开(公告)号： US08841295B2公开(公告)日： 2014-09-23
- 发明人: John H. Hutchinson , Yiwei Li , Mustapha Haddach , Nicholas Simon Stock
- 申请人： John H. Hutchinson , Yiwei Li , Mustapha Haddach , Nicholas Simon Stock
- 申请人地址： US CA San Diego
- 专利权人： Panmira Pharmaceuticals, LLC
- 当前专利权人： Panmira Pharmaceuticals, LLC
- 当前专利权人地址： US CA San Diego
- 代理机构： Goodrich & Rosati
- 代理商 Wilson Sonsini
- 国际申请： PCT/US2006/043095 WO 20061103
- 国际公布： WO2007/056220 WO 20070518
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D239/02 ; A61K31/4523 ; A61K31/427 ; C07D413/02 ; C07D401/02 ; C07D277/20 ; C07D209/04 ; C07D401/06 ; C07D401/10 ; C07D403/14 ; C07D413/14 ; C07D417/14 ; C07D405/14 ; C07D401/14 ; C07D471/04
摘要：
Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
公开/授权文献
- US20090221574A1 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors 公开/授权日：2009-09-03