发明授权
US08846698B2 Pyrrolo[2,3-d]pyrimidine tropomysin-related kinase inhibitors
有权
吡咯并[2,3-d]嘧啶与肌钙蛋白相关的激酶抑制剂
![Pyrrolo[2,3-d]pyrimidine tropomysin-related kinase inhibitors](/docs/US/2014-09-30/US08846698B2/abs.jpg.600x600.jpg)
- 专利标题： Pyrrolo[2,3-d]pyrimidine tropomysin-related kinase inhibitors
- 专利标题（中）： 吡咯并[2,3-d]嘧啶与肌钙蛋白相关的激酶抑制剂
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申请号： US13439131申请日： 2012-04-04
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公开(公告)号： US08846698B2公开(公告)日： 2014-09-30
- 发明人: Mark David Andrews , Sharanjeet Kaur Bagal , Karl Richard Gibson , Kiyoyuki Omoto , Thomas Ryckmans , Sarah Elizabeth Skerratt , Paul Anthony Stupple
- 申请人： Mark David Andrews , Sharanjeet Kaur Bagal , Karl Richard Gibson , Kiyoyuki Omoto , Thomas Ryckmans , Sarah Elizabeth Skerratt , Paul Anthony Stupple
- 申请人地址： US NY New York
- 专利权人： Pfizer Limited
- 当前专利权人： Pfizer Limited
- 当前专利权人地址： US NY New York
- 代理商 James T. Wasicak
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519 ; A61P25/04
![Pyrrolo[2,3-d]pyrimidine tropomysin-related kinase inhibitors](/abs-image/US/2014/09/30/US08846698B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as Trk antagonists.
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