发明授权
US08853215B2 Derivatives of N-acyl-N′-phenylpiperazine useful (inter alia) for the prophylaxis or treatment of diabetes
有权
N-酰基-N'-苯基哌嗪的衍生物可用于(尤其)用于预防或治疗糖尿病
- 专利标题: Derivatives of N-acyl-N′-phenylpiperazine useful (inter alia) for the prophylaxis or treatment of diabetes
- 专利标题(中): N-酰基-N'-苯基哌嗪的衍生物可用于(尤其)用于预防或治疗糖尿病
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申请号: US13264510申请日: 2010-04-16
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公开(公告)号: US08853215B2公开(公告)日: 2014-10-07
- 发明人: Shizuo Kasai , Kevin Francis McGee, Jr.
- 申请人: Shizuo Kasai , Kevin Francis McGee, Jr.
- 申请人地址: JP Osaka
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人地址: JP Osaka
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 国际申请: PCT/JP2010/057201 WO 20100416
- 国际公布: WO2010/119992 WO 20101021
- 主分类号: A61K31/495
- IPC分类号: A61K31/495 ; C07D295/00 ; C07D207/416 ; C07D335/02 ; C07D231/18 ; C07D295/215 ; C07D261/18 ; C07D209/24 ; C07D209/18 ; C07D295/185 ; C07D213/75 ; C07D211/88 ; C07D263/34 ; C07D513/04 ; C07D213/70 ; C07D213/65 ; C07D235/28 ; C07D233/72 ; C07D233/64 ; C07D307/24 ; C07D211/76 ; C07D231/14 ; C07D211/58 ; C07D233/90 ; C07D257/04 ; C07D211/46 ; C07D213/61 ; C07D261/12 ; C07D209/42 ; C07D207/16 ; C07D211/22 ; C07D307/30 ; C07D233/34 ; C07D309/38 ; C07D249/10 ; C07D211/34 ; C07D213/81 ; C07D207/26
摘要:
The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, which has a superior RBP4-lowering action and is useful as a pharmaceutical composition for the prophylaxis or treatment of a disease or condition mediated by an increase in RBP4.
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