Invention Grant
US08853277B2 Nitroxide therapy for the treatment of von Hippel—Lindau disease (VHL) and renal clear cell carcinoma (RCC)
有权
用于治疗von Hippel-Lindau病（VHL）和肾透明细胞癌（RCC）的硝酸处理
- Patent Title: Nitroxide therapy for the treatment of von Hippel—Lindau disease (VHL) and renal clear cell carcinoma (RCC)
- Patent Title (中): 用于治疗von Hippel-Lindau病（VHL）和肾透明细胞癌（RCC）的硝酸处理
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Application No.: US13512665Application Date: 2010-11-30
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Publication No.: US08853277B2Publication Date: 2014-10-07
- Inventor: W. Marston Linehan , Tracey A. Rouault , James Mitchell , Murali K. Cherukuri
- Applicant: W. Marston Linehan , Tracey A. Rouault , James Mitchell , Murali K. Cherukuri
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2010/058332 WO 20101130
- International Announcement: WO2011/066537 WO 20110603
- Main IPC: A61K31/13
- IPC: A61K31/13 ; A61K31/40 ; A61K31/445 ; A61K31/421
Abstract:
The invention provides therapeutic methods that include administering a stable nitroxide to a subject that has, is suspected to have, or is at risk for having a condition associated with reduced VHL or elevated HIF-2α.
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