Invention Grant
- Patent Title: 2,4-pyrimidinediamine compounds and their uses
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Application No.: US13759835Application Date: 2013-02-05
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Publication No.: US08853397B2Publication Date: 2014-10-07
- Inventor: Rajinder Singh , Ankush Argade , Donald G. Payan , Susan Molineaux , Sacha J. Holland , Jeffrey Clough , Holger Keim , Somasekhar Bhamidipati , Catherine Sylvain , Hui Li , Alexander B. Rossi
- Applicant: Rigel Pharmaceuticals, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmacuticals, Inc.
- Current Assignee: Rigel Pharmacuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Klarquist Sparkman, LLP
- Agent Travis Young
- Main IPC: C07D239/48
- IPC: C07D239/48 ; A61K31/506 ; C07D413/12 ; C07D401/12 ; A61K31/551 ; C07D409/12 ; C07D409/14 ; A61K31/538 ; C07D417/12 ; A61K31/519 ; C07D405/14 ; C07D401/14 ; C07D403/14 ; C07D265/36 ; A61K31/5383 ; A61K31/505 ; A61K45/06 ; C07D413/10 ; C07D413/14 ; A61K31/5377 ; C07D498/04 ; C07D405/12 ; C07D417/14 ; C07D403/12
Abstract:
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.
Public/Granted literature
- US20130150349A1 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES Public/Granted day:2013-06-13
Information query
