Invention Grant
US08858883B2 Method and system for capture and use of intact vesicles on electrodeposited hydrophobically modified biopolymer films
有权
在电沉积的疏水改性生物聚合物膜上捕获和使用完整囊泡的方法和系统
- Patent Title: Method and system for capture and use of intact vesicles on electrodeposited hydrophobically modified biopolymer films
- Patent Title (中): 在电沉积的疏水改性生物聚合物膜上捕获和使用完整囊泡的方法和系统
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Application No.: US13310579Application Date: 2011-12-02
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Publication No.: US08858883B2Publication Date: 2014-10-14
- Inventor: Matthew Dowling , Srinivasa R. Raghavan , Neeraja Dashaputre , Douglas Stephen English , Vishal Javvaji , Gregory F. Payne , Philip R. DeShong
- Applicant: Matthew Dowling , Srinivasa R. Raghavan , Neeraja Dashaputre , Douglas Stephen English , Vishal Javvaji , Gregory F. Payne , Philip R. DeShong
- Applicant Address: US MD College Park US KS Wichita
- Assignee: University of Maryland, College Park,Wichita State University
- Current Assignee: University of Maryland, College Park,Wichita State University
- Current Assignee Address: US MD College Park US KS Wichita
- Agency: Whiteford, Taylor & Preston, LLP
- Agent Joseph L. Morales
- Main IPC: G01N15/06
- IPC: G01N15/06 ; G01N33/00 ; G01N33/48 ; A61L15/44 ; A61F13/00 ; G01N33/543 ; A61L15/28 ; G01N33/548
Abstract:
A biosensor comprising an electrically conductive substrate coated with a modified chitosan biopolymer that has been electrodeposited on the substrate, wherein said modified chitosan biopolymer comprises at least one vesicle binding molecule. The biosensor is manufactured by a method where a modified chitosan biopolymer is electrodeposited on a substrate. The method is also used to manufacture a modified chitosan biopolymer film by electrodeposition of the chitosan on the substrate and later removing the film from the substrate after electrodeposition. The resulting film can be used in bandages to treat various types of wounds. The biosensor can also be used to detect various analytes in samples.
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