发明授权
US08859515B2 Treatment of tumor necrosis factor receptor 2 (TNFR2) related diseases by inhibition of natural antisense transcript to TNFR2
有权
通过抑制TNFR2的天然反义转录物治疗肿瘤坏死因子受体2（TNFR2）相关疾病
- 专利标题： Treatment of tumor necrosis factor receptor 2 (TNFR2) related diseases by inhibition of natural antisense transcript to TNFR2
- 专利标题（中）： 通过抑制TNFR2的天然反义转录物治疗肿瘤坏死因子受体2（TNFR2）相关疾病
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申请号： US13379728申请日： 2010-06-24
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公开(公告)号： US08859515B2公开(公告)日： 2014-10-14
- 发明人: Joseph Collard , Olga Khorkova Sherman
- 申请人： Joseph Collard , Olga Khorkova Sherman
- 申请人地址： US FL Miami
- 专利权人： CuRNA, Inc.
- 当前专利权人： CuRNA, Inc.
- 当前专利权人地址： US FL Miami
- 代理机构： CuRNA, Inc.
- 代理商 Monte R. Browder
- 国际申请： PCT/US2010/039824 WO 20100624
- 国际公布： WO2010/151671 WO 20101229
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; A61K31/711 ; C12Q1/68
摘要：
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Tumor Necrosis Factor Receptor 2 (TNFR2), in particular, by targeting natural antisense polynucleotides of Tumor Necrosis Factor Receptor 2 (TNFR2). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of TNFR2.
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