A method and apparatus for power control for wireless transmissions on multiple component carriers associated with multiple timing advances are disclosed. A wireless transmit/receive unit (WTRU) may perform power scaling or other adjustments on physical channels in each subframe to be transmitted on component carriers that belong to different timing advance groups (TAGs) if a sum of the transmit powers of the channels would or is to exceed a configured maximum output power for that subframe where each TAG may be associated with a separate timing advance value for uplink transmissions. The WTRU may adjust the transmit power of at least one physical channel if a sum of transmit powers in an overlapping portion of subframes of a less advanced TAG and a more advanced TAG would or is to exceed a configured maximum WTRU output power during the overlap.