发明授权
- 专利标题： B cell surface reactive antibodies
- 专利标题（中）： B细胞表面反应性抗体
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申请号： US13320630申请日： 2010-05-12
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公开(公告)号： US08877199B2公开(公告)日： 2014-11-04
- 发明人: Christoph Rader , Sivasubramanian Baskar , Michael R. Bishop , Ivan Samija , Jessica M. Suschak
- 申请人： Christoph Rader , Sivasubramanian Baskar , Michael R. Bishop , Ivan Samija , Jessica M. Suschak
- 申请人地址： US DC Washington
- 专利权人： The United States of America, as represented by the Secretary of the Department of Health and Human Services
- 当前专利权人： The United States of America, as represented by the Secretary of the Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Leydig, Voit & Mayer, Ltd.
- 国际申请： PCT/US2010/034491 WO 20100512
- 国际公布： WO2010/132532 WO 20101118
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/30 ; A61K51/10 ; C07K16/00 ; G01N33/574 ; G01N33/569
摘要：
The invention relates to antibodies that are reactive to the cell surface of CD19+ B cells, including B-cell chronic lymphocytic leukemia (B-CLL) cells, and compositions and methods for using such antibodies, including in the diagnosis and treatment of disorders associated with CD19+ B cells, such as B-CLL.
公开/授权文献
- US20120121504A1 B CELL SURFACE REACTIVE ANTIBODIES 公开/授权日：2012-05-17
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