While an electronic device with a display and a touch-sensitive surface is in a screen reader accessibility mode, the device displays an application launcher screen including a plurality of application icons. A respective application icon corresponds to a respective application stored in the device. The device detects a sequence of one or more gestures on the touch-sensitive surface that correspond to one or more characters. A respective gesture that corresponds to a respective character is a single finger gesture that moves across the touch-sensitive surface along a respective path that corresponds to the respective character. The device determines whether the detected sequence of one or more gestures corresponds to a respective application icon of the plurality of application icons, and, in response to determining that the detected sequence of one or more gestures corresponds to the respective application icon, performs a predefined operation associated with the respective application icon.