发明授权
US08889732B2 Fused heterocyclic compounds and thrombopoietin receptor activators
有权
稠合杂环化合物和血小板生成素受体激活剂
- 专利标题： Fused heterocyclic compounds and thrombopoietin receptor activators
- 专利标题（中）： 稠合杂环化合物和血小板生成素受体激活剂
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申请号： US13503560申请日： 2010-10-22
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公开(公告)号： US08889732B2公开(公告)日： 2014-11-18
- 发明人: Yukihiro Shigeta , Shingo Umezawa , Shunsuke Iwamoto , Takanori Nakamura
- 申请人： Yukihiro Shigeta , Shingo Umezawa , Shunsuke Iwamoto , Takanori Nakamura
- 申请人地址： JP Tokyo
- 专利权人： Nissan Chemical Industries, Ltd.
- 当前专利权人： Nissan Chemical Industries, Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权： JP2009-244852 20091023; JP2010-181032 20100812
- 国际申请： PCT/JP2010/068754 WO 20101022
- 国际公布： WO2011/049213 WO 20110428
- 主分类号： A61K31/38
- IPC分类号： A61K31/38 ; C07D333/32 ; C07D231/18 ; C07D333/38 ; C07D401/12 ; C07D409/12 ; C07D409/14 ; C07D409/04 ; C07D333/40
摘要：
Fused heterocyclic compounds useful for prevention, treatment or improvement of diseases against which activation of the thrombopoietin receptor is effective are provided.A compound represented by the formula (I) (wherein R1 is an aryl group fused to a saturated ring or the like, A, B, L1, R2, L2, L3, Y, L4, R3 and X are defined in the description), a tautomer, prodrug or a pharmaceutically acceptable salt of the compound or a solvate thereof.
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