Invention Grant
US08890216B2 Methods and apparatus for measuring analytes using large scale FET arrays
有权
使用大型FET阵列测量分析物的方法和设备
- Patent Title: Methods and apparatus for measuring analytes using large scale FET arrays
- Patent Title (中): 使用大型FET阵列测量分析物的方法和设备
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Application No.: US13909290Application Date: 2013-06-04
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Publication No.: US08890216B2Publication Date: 2014-11-18
- Inventor: Jonathan M. Rothberg , Wolfgang Hinz , Kim L. Johnson
- Applicant: Life Technologies Corporation
- Applicant Address: US CA Carlsbad
- Assignee: Life Technologies Corporation
- Current Assignee: Life Technologies Corporation
- Current Assignee Address: US CA Carlsbad
- Main IPC: H01L27/00
- IPC: H01L27/00 ; H01L51/00 ; G01N27/00 ; C12Q1/68 ; G01N27/414 ; H01L23/00 ; H01L21/306 ; H01L29/78

Abstract:
Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense arrays. Improved array control techniques provide for rapid data acquisition from large and dense arrays. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes. In one example, chemFET arrays facilitate DNA sequencing techniques based on monitoring changes in hydrogen ion concentration (pH), changes in other analyte concentration, and/or binding events associated with chemical processes relating to DNA synthesis.
Public/Granted literature
- US20130338046A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Public/Granted day:2013-12-19
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