A method of transmitting data for reducing interference in a hierarchical cell structure including a macro base station (BS) providing multi carriers and a femto BS providing a single carrier includes performing a channel scan within an interfered carrier to acquire channel state information and neighbor femto BS information if interference with the femto BS occurs; transmitting a channel measurement report including the channel state information and the neighbor femto BS information to the macro BS; and transmitting data through a carrier changed by receiving carrier change information from the macro BS.