Invention Grant
US08906282B2 Micro-structured and nano-structured surfaces on biodegradable polymers
有权
可生物降解聚合物上的微结构和纳米结构化表面
- Patent Title: Micro-structured and nano-structured surfaces on biodegradable polymers
- Patent Title (中): 可生物降解聚合物上的微结构和纳米结构化表面
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Application No.: US11176654Application Date: 2005-07-06
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Publication No.: US08906282B2Publication Date: 2014-12-09
- Inventor: Bee Eng Mary Chan , Jinye Shen , Bin He , Aiping Zhu , Yehai Yan , Chee Yoon Yue
- Applicant: Bee Eng Mary Chan , Jinye Shen , Bin He , Aiping Zhu , Yehai Yan , Chee Yoon Yue
- Applicant Address: SG Singapore
- Assignee: Nanyang Technological University
- Current Assignee: Nanyang Technological University
- Current Assignee Address: SG Singapore
- Agency: Blakely Sokoloff Taylor & Zafman LLP
- Main IPC: B27N3/08
- IPC: B27N3/08 ; B29C41/00 ; B28B7/30 ; A61F2/00 ; A61K9/14 ; B29C33/38 ; B29C33/42

Abstract:
In embodiments of the present invention, a biodegradable/biodegradable polymer film may be used as a scaffold for tissue engineering scaffolds for engineering organized organs, such as vascular grafts, for example. In one embodiment, an ultraviolet (UV) resin made from a diacrylated biodegradable oligomer is molded into a flexible scaffold having cavities and/or channels. Channel/cavity size may be on the order of micrometers and/or nanometers, and thus the walls may have high aspect ratios. Smooth muscle cells may be deposited in the channels and because of the high aspect ratios, the cells may align along the channels/cavities as confluence is reached.
Public/Granted literature
- US20070009572A1 Micro-structured and nano-structured surfaces on biodegradable polymers Public/Granted day:2007-01-11
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