Invention Grant
US08906371B2 Human anti-IFN-γ neutralizing antibodies as selective IFN-γ pathway inhibitors
有权
人抗IFN-γ中和抗体作为选择性IFN-γ途径抑制剂
- Patent Title: Human anti-IFN-γ neutralizing antibodies as selective IFN-γ pathway inhibitors
- Patent Title (中): 人抗IFN-γ中和抗体作为选择性IFN-γ途径抑制剂
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Application No.: US13966185Application Date: 2013-08-13
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Publication No.: US08906371B2Publication Date: 2014-12-09
- Inventor: Andrew A. Welcher , Hilary T. Chute , Yue-Sheng Li , Haichun Huang
- Applicant: Amgen, Inc. , Mederex, L.L.C.
- Applicant Address: US CA Thousand Oaks US NJ Princeton
- Assignee: Amgen Inc.,E.R. Squibb & Sons, L.L.C.
- Current Assignee: Amgen Inc.,E.R. Squibb & Sons, L.L.C.
- Current Assignee Address: US CA Thousand Oaks US NJ Princeton
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/24 ; C07K16/00 ; A61K39/00
Abstract:
This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-γ) and methods for treating IFN-γ mediated diseases by administering a pharmaceutically effective amount of antibodies to IFN-γ. Methods of detecting the amount of IFN-γ in a sample using antibodies to IFN-γ are also provided.
Public/Granted literature
- US20140004127A1 Human Anti-IFN-gamma Neutralizing Antibodies as Selective IFN-gamma Pathway Inhibitors Public/Granted day:2014-01-02
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