Invention Grant
US08906936B2 Pharmaceutical combination comprising co-administration of taxane and N-(1-cyclohexyl-2-{2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide or pharmaceutically acceptable salt(s) thereof
有权
药物组合包括联合给予紫杉烷和N-（1-环己基-2- {2- [4-（4-氟 - 苯甲酰基） - 噻唑-2-基] - 吡咯烷-1-基} -2-氧代 - 乙基）-2-甲基氨基 - 丙酰胺或其药学上可接受的盐
![Pharmaceutical combination comprising co-administration of taxane and N-(1-cyclohexyl-2-{2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide or pharmaceutically acceptable salt(s) thereof](/docs/US/2014-12-09/US08906936B2/abs.jpg.600x600.jpg)
- Patent Title: Pharmaceutical combination comprising co-administration of taxane and N-(1-cyclohexyl-2-{2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide or pharmaceutically acceptable salt(s) thereof
- Patent Title (中): 药物组合包括联合给予紫杉烷和N-（1-环己基-2- {2- [4-（4-氟 - 苯甲酰基） - 噻唑-2-基] - 吡咯烷-1-基} -2-氧代 - 乙基）-2-甲基氨基 - 丙酰胺或其药学上可接受的盐
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Application No.: US13761634Application Date: 2013-02-07
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Publication No.: US08906936B2Publication Date: 2014-12-09
- Inventor: Michael Rugaard Jensen , Christopher Sean Straub , Leigh Zawel , Mary Ann Tran , Youzhen Wang
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Jennifer Chapman
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; A61K31/16 ; A61K31/425 ; A61K45/06 ; A61K31/437 ; A61K31/475 ; C07D471/04 ; A61K31/337
![Pharmaceutical combination comprising co-administration of taxane and N-(1-cyclohexyl-2-{2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide or pharmaceutically acceptable salt(s) thereof](/abs-image/US/2014/12/09/US08906936B2/abs.jpg.150x150.jpg)
Abstract:
The invention provides a pharmaceutical combination comprising: a) compounds that inhibit the binding of the Smac protein to IAPs; and b) a taxane, and a method for treating or preventing a proliferative disease using such a combination.
Public/Granted literature
- US20130217719A1 Combination of Organic Compounds Public/Granted day:2013-08-22
Information query
IPC分类:
