发明授权
- 专利标题： Modulation of CD40 expression
- 专利标题（中）： 调节CD40表达
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申请号： US12743797申请日： 2008-11-20
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公开(公告)号： US08916531B2公开(公告)日： 2014-12-23
- 发明人: C. Frank Bennett , Lex M. Cowsert , Susan M. Freier
- 申请人： C. Frank Bennett , Lex M. Cowsert , Susan M. Freier
- 申请人地址： US CA Carlsbad
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Carlsbad
- 代理机构： Isis Pharmacueticals, Inc. Patent Dept.
- 国际申请： PCT/US2008/012998 WO 20081120
- 国际公布： WO2009/067243 WO 20090528
- 主分类号： C12N15/113
- IPC分类号： C12N15/113
摘要：
Disclosed herein are antisense compounds and methods for decreasing CD40. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to CD40 include hyperproliferative disorders, graft versus host disease (GVHD), graft rejection, asthma, airway hyperresponsiveness, chronic obstructive pulmonary disease (COPD), multiple sclerosis (MS), systemic lupus erythematosus (SLE), and certain forms of arthritis.
公开/授权文献
- US20110160283A1 MODULATION OF CD40 EXPRESSION 公开/授权日：2011-06-30
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