Invention Grant
- Patent Title: Monocyclic pyridine derivative
- Patent Title (中): 单环吡啶衍生物
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Application No.: US14183864Application Date: 2014-02-19
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Publication No.: US08933099B2Publication Date: 2015-01-13
- Inventor: Setsuo Funasaka , Toshimi Okada , Keigo Tanaka , Satoshi Nagao , Isao Ohashi , Yoshinobu Yamane , Yusuke Nakatani , Yuki Karoji
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- Main IPC: A61K31/445
- IPC: A61K31/445 ; C07D401/14 ; C07D409/14 ; C07D401/12

Abstract:
The present invention provides a novel compound having FGFR inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same. Specifically, the present invention provides a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: wherein n represents 0 to 2; A represents an arylene group or a heteroarylene group; G represents a single bond, an oxygen atom or —CH2—; E represents a nitrogen-containing non-aromatic heterocycle; R1 represents an alkoxy group or the like; R2 represents a hydrogen atom or the like; and R3 represents a hydrogen atom, an alkyl group, an alkoxy group or the like, with the proviso that when E represents an azetidine ring and R2 or R3 is present on a nitrogen atom on the azetidine ring, the R2 or R3 does not represent a hydrogen atom.
Public/Granted literature
- US20140235614A1 MONOCYCLIC PYRIDINE DERIVATIVE Public/Granted day:2014-08-21
Information query
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