Invention Grant
- Patent Title: Glucagon receptor modulators
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Application No.: US14334718Application Date: 2014-07-18
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Publication No.: US08933104B2Publication Date: 2015-01-13
- Inventor: Gary Erik Aspnes , Mary Theresa Didiuk , Kevin James Filipski , Angel Guzman-Perez , Jeffrey Allen Pfefferkorn , Benjamin Dawson Stevens , Meihua Mike Tu
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent James T. Wasicak
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/44 ; C07D213/82

Abstract:
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
Public/Granted literature
- US20140329862A1 Glucagon Receptor Modulators Public/Granted day:2014-11-06
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