发明授权
- 专利标题： Macrocyclic hepatitis C serine protease inhibitors
- 专利标题（中）： 大环丙型肝炎丝氨酸蛋白酶抑制剂
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申请号： US13339440申请日： 2011-12-29
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公开(公告)号： US08937041B2公开(公告)日： 2015-01-20
- 发明人: Keith F. McDaniel , Hui-Ju Chen , Ming Yeung , Timothy Middleton , Liangjun Lu , Kevin Kurtz
- 申请人： Keith F. McDaniel , Hui-Ju Chen , Ming Yeung , Timothy Middleton , Liangjun Lu , Kevin Kurtz
- 申请人地址： US IL North Chicago
- 专利权人： AbbVie, Inc.
- 当前专利权人： AbbVie, Inc.
- 当前专利权人地址： US IL North Chicago
- 代理机构： Edwards Wildman Palmer LLP
- 代理商 Jeffrey D. Hsi; Stephen W. Rafferty
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K5/08 ; C07K5/083
摘要：
The present invention relates to novel fluorinated macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
公开/授权文献
- US20120172291A1 MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS 公开/授权日：2012-07-05
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