发明授权
US08937076B2 Crystalline form of entecavir, its preparation and the pharmaceutical composition and uses thereof
有权
恩替卡韦的结晶形式及其制备及其药物组合物及其用途
- 专利标题： Crystalline form of entecavir, its preparation and the pharmaceutical composition and uses thereof
- 专利标题（中）： 恩替卡韦的结晶形式及其制备及其药物组合物及其用途
-
申请号： US12527215申请日： 2008-01-31
-
公开(公告)号： US08937076B2公开(公告)日： 2015-01-20
- 发明人: Weidong Ye , Jianyong Yuan , Jingjing Nie , Duanjun Xu , Chaotian Chen
- 申请人： Weidong Ye , Jianyong Yuan , Jingjing Nie , Duanjun Xu , Chaotian Chen
- 申请人地址： CN
- 专利权人： Zhejiang Medicine Co., Ltd. Xinchang Pharaceutical Factory
- 当前专利权人： Zhejiang Medicine Co., Ltd. Xinchang Pharaceutical Factory
- 当前专利权人地址： CN
- 代理机构： McNeely, Hare & War, LLP
- 代理商 William D. Hare, Esq.
- 优先权： CN200710004988 20070214
- 国际申请： PCT/CN2008/000249 WO 20080131
- 国际公布： WO2008/098471 WO 20080821
- 主分类号： A61K31/522
- IPC分类号： A61K31/522 ; C07D473/18
摘要：
The present invention relates to a crystalline form of entecavir and its process for preparation, and provides a pharmaceutical composition comprising a therapeutically effective amount of the crystalline form of entecavir. Furthermore, the present invention also provides a use of the crystalline form of entecavir in preparation for a medicament for the treatment of hepatitis B viral infections. The present invention is beneficial toe preparations for pharmaceutical formulations and enhancements of its bioavailability.
公开/授权文献
信息查询
IPC分类:
