发明授权
- 专利标题: Medium-chain length fatty acids, salts and triglycerides in combination with gemcitabine for treatment of pancreatic cancer
- 专利标题(中): 中链长度脂肪酸,盐和甘油三酯与吉西他滨联合治疗胰腺癌
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申请号: US12809380申请日: 2008-12-18
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公开(公告)号: US08946190B2公开(公告)日: 2015-02-03
- 发明人: Lyne Gagnon , Lilianne Geerts , Christopher Penney
- 申请人: Lyne Gagnon , Lilianne Geerts , Christopher Penney
- 申请人地址: CA Mont-Royal, Quebec
- 专利权人: Prometic Biosciences Inc.
- 当前专利权人: Prometic Biosciences Inc.
- 当前专利权人地址: CA Mont-Royal, Quebec
- 代理机构: Clark & Elbing LLP
- 国际申请: PCT/CA2008/002190 WO 20081218
- 国际公布: WO2009/076761 WO 20090625
- 主分类号: A61K31/7068
- IPC分类号: A61K31/7068 ; A61K31/517 ; A61K31/23 ; A61K31/20 ; A61P35/00
摘要:
The present invention relates to the use of medium-chain length fatty acids of formula I, triglycerides of formula 2 (wherein n=6-10), salts thereof, or mixtures thereof, in combination with gemcitabine and optionally erlotinib in the treatment of pancreatic cancer in human patients. Exemplary medium-chain length fatty acid/triglyceride compounds include capric acid, sodium caprate, tricaprin, lauric acid, sodium laurate, and trilaurin.
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