Invention Grant
US08952180B2 Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
有权
吡咯烷酮甲酰胺化合物可用作内皮脂肪酶抑制剂
- Patent Title: Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
- Patent Title (中): 吡咯烷酮甲酰胺化合物可用作内皮脂肪酶抑制剂
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Application No.: US14346745Application Date: 2012-09-25
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Publication No.: US08952180B2Publication Date: 2015-02-10
- Inventor: Lynn Abell , Leonard Adam , Cullen L. Cavallaro , Heather Finlay , Todd J. Friends , Jon J. Hangeland , Ji Jiang , R. Michael Lawrence , John Lloyd , Zulan Pi , George O. Tora , Jennifer X. Qiao , Carol Hui Hu , Tammy C. Wang
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Jing G. Sun
- International Application: PCT/US2012/056990 WO 20120925
- International Announcement: WO2013/048982 WO 20130404
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/40 ; C07D221/02 ; C07D205/00 ; C07D207/38 ; C07D403/12 ; C07D401/06 ; C07D401/12 ; C07D403/04 ; C07D403/06 ; C07D405/06 ; C07D405/12 ; C07D417/04 ; C07D417/06 ; C07D471/04 ; C07D207/28 ; C07D417/12 ; C07D487/04
Abstract:
The present invention provides compounds of Formula (I) or Formula (III): [INSERT CHEMICAL STRUCTURE HERE] (I) [INSERT CHEMICAL STRUCTURE HERE] (III) as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicaments.
Public/Granted literature
- US20140221357A1 PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS Public/Granted day:2014-08-07
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