发明授权
- 专利标题: Methods for identifying allosteric modulators of ship polypeptides
- 专利标题(中): 识别船舶多肽变构调节剂的方法
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申请号: US12478402申请日: 2009-06-04
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公开(公告)号: US08956824B2公开(公告)日: 2015-02-17
- 发明人: Alice Mui , Christopher Ong , Gerald Krystal , Raymond Andersen
- 申请人: Alice Mui , Christopher Ong , Gerald Krystal , Raymond Andersen
- 申请人地址: CA Vancouver, BC
- 专利权人: British Columbia Cancer Agency Branch
- 当前专利权人: British Columbia Cancer Agency Branch
- 当前专利权人地址: CA Vancouver, BC
- 代理机构: Greenberg Traurig, LLP
- 代理商 Chinh H. Pham; Fang Xie
- 主分类号: C12Q1/42
- IPC分类号: C12Q1/42 ; G01N33/53 ; C07K14/00 ; A61K39/00 ; G01N33/573
摘要:
This invention provides a method for identifying allosteric modulators of a SHIP polypeptide, wherein said SHIP polypeptide is contacted with a test compound, and wherein said SHIP polypeptide comprises an allosteric site selected from the group consisting of a SHIP C2 domain and a SHIP PH domain.
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