Invention Grant
US08961878B2 Label-free cellular manipulation and sorting via biocompatible ferrofluids 有权
通过生物相容的铁磁流体进行无标记的细胞操纵和分选

  • Patent Title: Label-free cellular manipulation and sorting via biocompatible ferrofluids
  • Patent Title (中): 通过生物相容的铁磁流体进行无标记的细胞操纵和分选
  • Application No.: US13514331
    Application Date: 2010-12-07
  • Publication No.: US08961878B2
    Publication Date: 2015-02-24
  • Inventor: Hur Koser
  • Applicant: Hur Koser
  • Applicant Address: US CT New Haven
  • Assignee: Yale University
  • Current Assignee: Yale University
  • Current Assignee Address: US CT New Haven
  • Agency: Riverside Law LLP
  • International Application: PCT/US2010/059270 WO 20101207
  • International Announcement: WO2011/071912 WO 20110616
  • Main IPC: G01N33/00
  • IPC: G01N33/00 G01N27/26 B03C1/253 B01D35/06
Label-free cellular manipulation and sorting via biocompatible ferrofluids
Abstract:
A device for separating a sample of cells suspended in a bio-compatible ferrofluid is described. The device includes a microfluidic channel having a sample inlet, at least one outlet and a length between the same inlet and the at least one outlet, wherein a sample can be added to the sample inlet and flow along the microfluidic channel length to the at least one outlet. The device includes a plurality of electrodes and a power source for applying a current to the plurality of electrodes to create a magnetic field pattern along the microfluidic channel length. The present invention also includes a method of using said device for separating at least one cell type.
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