Invention Grant
- Patent Title: Synthetic analogs of sphingolipids
- Patent Title (中): 鞘脂的合成类似物
-
Application No.: US12742045Application Date: 2008-11-09
-
Publication No.: US08962891B2Publication Date: 2015-02-24
- Inventor: Arie Dagan , Shimon Slavin , Shimon Gatt , Jeremy Zahavi
- Applicant: Arie Dagan , Shimon Slavin , Shimon Gatt , Jeremy Zahavi
- Applicant Address: IL Jerusalem IL Jerusalem
- Assignee: Hadasit Medical Research Services & Development Limited,Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd.
- Current Assignee: Hadasit Medical Research Services & Development Limited,Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd.
- Current Assignee Address: IL Jerusalem IL Jerusalem
- Agency: Hunton & Williams LLP
- Priority: IL187247 20071108
- International Application: PCT/IL2008/001472 WO 20081109
- International Announcement: WO2009/060457 WO 20090514
- Main IPC: C07C215/10
- IPC: C07C215/10 ; A61K31/13
Abstract:
The present invention provides new ceramide analogs indicated as the compounds of formula (II). These novel analogs exhibit a significant anti cancerous effect and are therefore provided as a pharmaceutical composition for treating cell proliferative diseases, neurodegenerative disorders, metabolism-associated conditions, infectious diseases, and immune-related disorders. The invention further provides combined compositions and kits combining the novel ceramide analogs of formula (II) with an additional therapeutic agent.
Public/Granted literature
- US20110034542A1 NOVEL SYNTHETIC ANALOGS OF SPHINGOLIPIDS Public/Granted day:2011-02-10
Information query
