Systems and methods are provided for configuring settings of a mobile device based on an inferred location. The mobile device can use stored indicia of trip (e.g., an electronic ticket or itinerary) to identify origination and destination locations. The start and end of the trip can be inferred based on changes in operation of the mobile device. For instance, if the user is on an airplane, the user may turn off network connectivity at the origination location just prior to takeoff, and may turn the network connectivity back on upon landing at the destination location. If the time that elapsed between the changes in operation is consistent with the duration of the trip indicated by the stored indicia, the mobile device can infer that the current location is the destination location. The mobile device can then configure location-specific settings in accordance with the destination location to establish a network connection.