发明授权
US08969311B2 Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide
有权
具有抗菌活性和血管生成诱导活性的多肽和含有所述多肽的伤口愈合药物
- 专利标题： Polypeptide having antibacterial activity and angiogenesis-inducing activity and wound-healing drug containing said polypeptide
- 专利标题（中）： 具有抗菌活性和血管生成诱导活性的多肽和含有所述多肽的伤口愈合药物
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申请号： US13322424申请日： 2010-05-25
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公开(公告)号： US08969311B2公开(公告)日： 2015-03-03
- 发明人: Takefumi Gemba , Hideki Tomioka , Nao Tamura , Ryoko Sata , Akito Maeda , Akiko Tenma , Toshihide Kanamori , Yoshimi Saito , Shintaro Komaba , Ryuichi Morishita
- 申请人： Takefumi Gemba , Hideki Tomioka , Nao Tamura , Ryoko Sata , Akito Maeda , Akiko Tenma , Toshihide Kanamori , Yoshimi Saito , Shintaro Komaba , Ryuichi Morishita
- 申请人地址： JP Osaka
- 专利权人： AnGes MG, Inc.
- 当前专利权人： AnGes MG, Inc.
- 当前专利权人地址： JP Osaka
- 代理机构： Law Office of: Michael A. Sanzo, LLC
- 优先权： JP2009-125072 20090525
- 国际申请： PCT/JP2010/058838 WO 20100525
- 国际公布： WO2010/137594 WO 20101202
- 主分类号： A61K38/10
- IPC分类号： A61K38/10 ; A61K38/16 ; A61P35/00 ; C07K14/515 ; A61K38/00 ; A61K38/04 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00 ; C07K7/08
摘要：
A novel polypeptide which has an excellent angiogenesis-inducing activity and an excellent antibacterial activity, and a novel angiogenesis-inducing agent which contains the polypeptide as an effective ingredient or a novel agent for treating a wound(s) which contains the polypeptide as an effective ingredient are disclosed. The polypeptide of the present invention is a polypeptide whose amino acid sequence is shown in any one of SEQ ID NOs:1 to 6, 8 and 10. The angiogenesis-inducing agent which contains the polypeptide of the present invention as an effective ingredient is useful for the prevention, amelioration or treatment of a disease such as a burns, decubitus, wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease and arteriosclerosis obliteran.
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