发明授权
US08974783B2 Methods of treating pain using an IL-31Ra or OSMR-b antagonist
有权
使用IL-31Ra或OSMR-b拮抗剂治疗疼痛的方法
- 专利标题: Methods of treating pain using an IL-31Ra or OSMR-b antagonist
- 专利标题(中): 使用IL-31Ra或OSMR-b拮抗剂治疗疼痛的方法
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申请号: US14175117申请日: 2014-02-07
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公开(公告)号: US08974783B2公开(公告)日: 2015-03-10
- 发明人: Yue Yao , Janine Bilsborough
- 申请人: ZymoGenetics, Inc.
- 申请人地址: US NJ Princeton
- 专利权人: ZymoGenetics, Inc.
- 当前专利权人: ZymoGenetics, Inc.
- 当前专利权人地址: US NJ Princeton
- 代理商 Brian J. Walsh
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/28 ; A61K38/17 ; C07K16/24 ; A61K39/00
摘要:
Use of antagonists to IL-31Ra and OSMRb are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such antagonists include soluble receptors, antibodies and fragments, derivative, or variants thereof. Symptoms such as pain, tingle, sensitization, tickle associated with neuropathies are ameliorated.
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